Give as directed by your veterinarian. Follow the instructions printed on the prescription label. Store doxycycline at room temperature. Be sure to complete the prescription to ensure a full recovery, even if your pet seems to be improving, unless instructed otherwise by your veterinarian. Allow your pet access to plenty of water. Doxycycline can be given with or without food but should not be given with dairy products.
Keep out of the reach of children and pets. Do not use in animals with a known sensitivity to doxycycline. Do not use in pregnant animals. Let your veterinarian know if your pet is on any other medications, as interactions with certain medicines can occur. Do not administer any calcium-containing medications, antacids, laxatives, or multivitamins within 2 hours of the last doxycycline dose. Notify your veterinarian if your animal suffers from kidney or liver disease. Doxycycline may increase skins sensitivity to sunlight. Store at room temperature. Store protected from light and moisture.
Allergic reactions and serious side effects are rare, but in the case of an allergic reaction or a serious side effect you should stop doxycycline treatment and seek veterinary attention. Some common signs of allergic reactions and serious side effects are hives, breathing difficulty, facial swelling, loss of appetite, or dark colored urine.
Should be stored at room temperature, away from moisture and heat.
Doxycycline should not be used in animals allergic to it or other tetracycline antibiotics. Use with caution in animals with impaired liver or kidney function. Do not use in pregnant, nursing, or growing animals since this medication may cause slowing of bone growth and discoloration of teeth. Give antacids, vitamin and mineral combinations, iron, or Pepto-Bismol at least 1 hour before or 4 hours after giving doxycycline. Use caution when given with digoxin or warfarin. Doxycycline is not affected by food.
iosyncradoresinaeIn a retrospective analysis, patients treated with doxycycline therapy for 14 years were randomized to receive a group of intravenous doxycycline at 100 mg/kg/day for 12 to 21 days. They also received oral doxycycline or a combination of the two drugs. Doxycycline was the standard therapy for treating the primary indication of treatment, but was also used for secondary prevention of infection.
The primary outcome was clinical worsening. Secondary outcomes were the need for a second course of antibiotic treatment and the incidence of severe infection. Secondary outcomes were the time to clinical worsening and the time to antibiotic treatment failure.
The secondary outcome included the occurrence of antibiotic-related adverse events (AEs).
The primary outcomes were the time to clinical worsening. Secondary outcomes included the time to antibiotic treatment failure.
The following are the primary endpoints:
The time to the clinical worsening (on day 0), hospitalization for infection, and the need for a second course of antibiotics (included in the secondary endpoints);
Patients with severe infections had to be treated with a single dose of doxycycline.
The time to the first episode of infection was defined as the number of days the patient was treated with doxycycline during the 14 years of observation.
The time to the second episode of infection was defined as the number of days the patient was treated with doxycycline during the 14 years of observation.
tell your doctor and pharmacist if you are allergic to doxycycline, minocycline, tetracycline, demeclocycline, any other medications, sulfites, or any of the ingredients in doxycycline capsules, extended-release capsules, tablets, extended-release tablets, or suspension. Ask your pharmacist for a list of the ingredients.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: acitretin (Soriatane); anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); barbiturates such as butabarbital (Butisol), phenobarbital, and secobarbital (Seconal); bismuth subsalicylate; carbamazepine (Epitol, Tegretol, others); isotretinoin (Absorica, Amnesteem, Clavaris, Myorisan, Zenatane); penicillin; phenytoin (Dilantin, Phenytek); and proton pump inhibitors such as dexlansoprazole (Dexilant), esomeprazole (Nexium, in Vimovo), lansoprazole (Prevacid, in Prevpac), omeprazole (Prilosec, in Yosprala, Zegerid), pantoprazole (Protonix), and rabeprazole (Aciphex). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
be aware that antacids containing magnesium, aluminum, or calcium, calcium supplements, iron products, and laxatives containing magnesium interfere with doxycycline, making it less effective. Take doxycycline 2 hours before or 6 hours after taking antacids, calcium supplements, and laxatives containing magnesium. Take doxycycline 2 hours before or 4 hours after iron preparations and vitamin products that contain iron.
tell your doctor if you have or have ever had lupus (condition in which the immune system attacks many tissues and organs including the skin, joints, blood, and kidneys), intracranial hypertension (pseudotumor cerebri; high pressure in the skull that may cause headaches, blurry or double vision, vision loss, and other symptoms), a yeast infection in your mouth or vagina, surgery on your stomach, asthma, or kidney or liver disease.
you should know that doxycycline may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, or injections). Talk to your doctor about using another form of birth control.
tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking doxycycline, call your doctor immediately. Doxycycline can harm the fetus.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Doxycycline may make your skin sensitive to sunlight. Tell your doctor right away if you get a sunburn.
you should know that when doxycycline is used during pregnancy or in babies or children up to 8 years of age, it can cause the teeth to become permanently stained. Doxycycline should not be used in children under 8 years of age except for inhalational anthrax, Rocky Mountain spotted fever, or if your doctor decides it is needed.
All brand name Cetirizine products are available without a prescription. Doxycycline, minocycline, and tetracycline are nonprescription medications used to treat bacterial infections. Doxycycline is a tetracycline antibiotic that binds to bacteria cell death receptors and prevents them from making proteins that then kill them. Doxycycline may also reduce the effectiveness of hormonal contraceptives (birth control pills, patches, rings, or injections). You should not take doxycycline if you are taking or have recently taken doxycycline because it can cause serious skin reactions and other factors to become serious. You should talk to your doctor about taking doxycycline if you are taking or have recently taken any of the medications listed in the IMPORTANT WARNING section.
How to use doxycycline:Use doxycycline exactly as directed by your doctor. Do not take more or less of it or take it more often than prescribed by your doctor. Follow the instructions provided by your doctor.
Malaria is a serious tropical disease spread by mosquitoes. If it isn’t diagnosed and treated promptly, it can be fatal.
A single mosquito bite is all it takes for someone to become infected.
Symptoms of malaria
It’s important to be aware of the symptoms of malaria if you’re travelling to areas where there’s a high risk of the disease. Symptoms include:
a high temperature (fever) sweats and chills headaches vomiting muscle pains diarrhoea Symptoms usually appear between 7 and 18 days after becoming infected, but in some cases the symptoms may not appear for up to a year, or occasionally even longer.
When to seek medical attention
Seek medical help immediately if you develop symptoms of malaria during or after a visit to an area where the disease is found.
Malaria risk areas
Malaria is found in more than 100 countries, mainly in tropical regions of the world, including:
large areas of Africa and Asia Central and South America Haiti and the Dominican Republic parts of the Middle East some Pacific islands
Thehas more information about the risk of malaria in specific countries.
Preventing malaria
Many cases of malaria can be avoided. An easy way to remember is the ABCD approach to prevention:
Awareness of risk – find out whether you’re at risk of getting malaria before travelling Bite prevention – avoid mosquito bites by using insect repellent, covering your arms and legs, and using an insecticide-treated mosquito net Check whether you need to take malaria prevention tablets – if you do, make sure you take the right antimalarial tablets at the right dose, and finish the course Diagnosis – seek immediate medical advice if you develop malaria symptoms, as long as up to a year after you return from travelling
Side effects
Like all medicines, doxycycline can cause side effects, although not everyone gets them.
Common side effects These common side effects happen in around 1 in 10 people. Keep taking the medicine, but talk to your doctor or pharmacist if these side effects bother you or don’t go away:
a headache feeling sick or vomiting being sensitive to sunlight Serious side effects Serious side effects are rare and happen in less than 1 in 1,000 people.
Call a doctor straight away if you get:
Bruising or bleeding you can’t explain (including nosebleeds), a sore throat, a high temperature (38C or above) and you feel tired or generally unwell – these can be signs of blood problems.
Severe diarrhoea (perhaps with stomach cramps) that contains blood or mucus, or lasts longer than 4 days ringing or buzzing in your ears
Serious skin reactions or rashes, including irregular, round red patches, peeling, blisters, skin ulcers, or swelling of the skin that looks like burns – these could be signs of a rare reaction to the medicine called Stevens-Johnson Syndrome
Yellow skin or the whites of your eyes go yellow – this could be a sign of liver problems joint or muscle pain that has started since you began taking doxycycline
Headache, vomiting and problems with your vision – these could be signs of pressure around your brain (intracranial hypertension)
A fingernail coming away from its base – this could be a reaction to sunlight called photo-onycholysis
A sore or swollen mouth, lips or tongue
Severe pain in your tummy, with or without bloody diarrhoea, feeling sick and being sick – these can be signs of pancreatitis difficulty or pain when you swallow, a sore throat, acid reflux, a smaller appetite or chest pain which gets worse when you eat – these could be signs of an inflamed food pipe (oesophagitis) or oesophageal ulcer
Serious allergic reactions
Allergic reactions to doxycycline are common and occur in more than 1 in 100 people.
These are not all the side effects of doxycycline.
You can report any suspected side effect to the UK.